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Was (wer) ist purine-nucleoside phosphorylase - definition
INTERPRO FAMILY
Nucleoside phosphorylase; Purine-nucleoside phosphorylase; NP (gene); PNP (gene); EC 2.4.2.1; PUNPI; Purine-nucleoside:phosphate ribosyltransferase
![One of the reaction catalyzed by purine nucleoside phosphorylase in [[purine metabolism]]](https://commons.wikimedia.org/wiki/Special:FilePath/Purine-nucleoside phosphate ribosyltransferase.png?width=200 "One of the reaction catalyzed by purine nucleoside phosphorylase in [[purine metabolism]]")
Purine nucleoside phosphorylase deficiency
COMBINED T CELL AND B CELL IMMUNODEFICIENCY THAT IS A RARE AUTOSOMAL RECESSIVE METABOLIC DISORDER THAT HAS MATERIAL BASIS IN MUTATION IN THE PNP GENE AND CHARACTERIZED MAINLY BY DECREASED T-CELL FUNCTION
Purine nucleoside phosphorylase deficiency is a rare autosomal recessive metabolic disorder which results in immunodeficiency.
Diphosphate-purine nucleoside kinase
CLASS OF ENZYMES
EC 2.7.1.143; Diphosphate:purine nucleoside phosphotransferase
In enzymology, a diphosphate-purine nucleoside kinase () is an enzyme that catalyzes the chemical reaction
Purine metabolism
THE CHEMICAL REACTIONS AND PATHWAYS INVOLVING PURINE NUCLEOTIDES
Purine biosynthesis; Purine degradation; Purine synthesis inhibitors; Purine inhibitors; Purine synthesis inhibitor; Adenine pathway
Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms.
Wikipedia
Purine nucleoside phosphorylase
Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene. It catalyzes the chemical reaction
- purine nucleoside + phosphate purine + alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are a purine nucleoside and phosphate, whereas its products are a purine and alpha-D-ribose 1-phosphate.
